Combined Arterial and Venous Thrombosis in Ulcerative Colitis- A Rare Vascular Manifestation
Published: April 1, 2016 | DOI: https://doi.org/10.7860/JCDR/2016/.7608
Harpreet Singh, Pranav Ish, Richa Dewan, S Anuradha, Sumeet Singla
1. Senior Resident, Department of Medicine, Maulana Azad Medical College and Lok Nayak Hospital, New Delhi, India.
2. Post Graduate Resident, Department of Medicine, Maulana Azad Medical College and Lok Nayak Hospital, New Delhi, India.
3. Director Professor, Department of Medicine, Maulana Azad Medical College and Lok Nayak Hospital, New Delhi, India.
4. Professor, Department of Medicine, Maulana Azad Medical College and Lok Nayak Hospital, New Delhi, India.
5. Assistant Professor, Department of Medicine, Maulana Azad Medical College and Lok Nayak Hospital, New Delhi, India.
Correspondence
Dr. Pranav Ish,
B1, 1st Floor, Green Park Extension, New Delhi -110016, India.
E-mail: pranavish2512@gmail.com
Combined arterial and venous thrombosis in patients with ulcerative colitis is a rare extra vascular manifestation, which motivated the current report. Increased coagulability is a recognised feature of ulcerative colitis with frequency increasing during flares. We report the case of a 42-year-old lady who was a diagnosed case of ulcerative colitis, currently in remission. She presented with swelling followed by discolouration of left lower limb which later was diagnosed as deep venous thrombosis combined with femoral and popliteal artery thrombosis. This led to wet gangrene of the limb, sepsis, septic shock and death despite aggressive management with heparin infusion, ionotropes, and parenteral antibiotics therapy.
[
FULL TEXT ] | [ PDF]